Within MISIT we aim to improve minimally invasive surgery, flexible endoscopy, needle interventions, endovascular interventions. We are cooperating with surgeons of several (university) hospitals, e.g. Leiden University Medical Center, Erasmus Medical Center Rotterdam, Reinier de Graaf Gasthuis Delft, Academic Medical Center Amsterdam.  Our research projects are in the fields of designing novel medical instruments, medical haptics, training and simulation systems, and patient safety, with the focus on minimally invasive techniques. Recently a number of projects started to develop affordable and high quality (minimally invasive) surgical instruments for low and middle income countries.